신약개발 소식, 해외 논문들

Asco 2021 – the exon 20 army lines up behind Rybrevant

stayalive1 2021. 10. 17. 05:46

https://www.evaluate.com/vantage/articles/events/conferences/asco-2021-exon-20-army-lines-behind-rybrevant

 

Asco 2021 – the exon 20 army lines up behind Rybrevant

A new lung cancer niche is a major focus of Asco, with China's Dizal perhaps boasting the most intriguing dataset.

www.evaluate.com

Amivantamab(Rybrevant, Janssen) : egfr & Met

  https://en.wikipedia.org/wiki/Amivantamab : 2021.5  FDA 승인

  https://www.clinicaloptions.com/oncology/programs/2021/nsclc-biomarker-advances-2021/downloadable-slidesets/slideset2

  https://blog.naver.com/kmalsh/222426565528

 

DZD9008(Dizal, China)

  https://www.clinicaloptions.com/oncology/conference-coverage/2021/wclc-2021/wclc-highlights/capsule-summary-slidesets/oa15_02

  https://m.healthcaren.com/news/news_article_yong.jsp?mn_idx=365978  

  https://www.mdalert.com/article/targeted-therapy-for-nsclc-subgroup-1-1

 

CLN-081(Zai Lab, China)

  https://www.clinicaloptions.com/oncology/programs/2021/nsclc-biomarker-advances-2021/on-demand-webcast/webcast

https://zailab.gcs-web.com/news-releases/news-release-details/zai-lab-and-cullinan-oncology-announce-strategic-collaboration

 

Mobocertinib(Exkivity,Takeda Pharmaceuticals, Inc.) : irreversible kinase inhibitor, a first-in-class oral treatment, 

  https://en.wikipedia.org/wiki/Mobocertinib : 2021.9 FDA 승인

  https://www.clinicaloptions.com/oncology/programs/2021/nsclc-biomarker-advances-2021/downloadable-slidesets/slideset2

  http://www.yakup.com/news/index.html?mode=view&nid=261293 

 

 

BDTX-189 ( Black Diamond Therapeutics, Inc.): selective inhibitor of allosteric EGFR and HER2

  https://www.medchemexpress.com/bdtx-189.html?locale=ko-KR?src=google-product?src=google-product&gclid=CjwKCAjw8KmLBhB8EiwAQbqNoLdWdi8MpCNH_MOPEuYmguPe0wVF3AD1T7n0KloL80QO_7lH7ERJSBoCSgMQAvD_BwE 

 

Poziotinib (한미약품)

 https://en.wikipedia.org/wiki/Poziotinib

    https://www.clinicaloptions.com/oncology/conference-coverage/wclc-2018/capsule-summary-slidesets/oa02_06

    https://www.selleckchem.com/products/poziotinib-hm781-36b.html

    http://www.biospectator.com/view/news_view.php?varAtcId=14354 

    http://www.biospectator.com/view/news_view.php?varAtcId=14349

 

My Thoughts on Recently Approved Therapies for EGFR Exon 20 Insertion Mutation–Positive Advanced NSCLC

https://www.clinicaloptions.com/oncology/programs/2021/nsclc-egfr-ex20/clinicalthought/ct2/page-1

 

ClinicalThought - EGFR ex20ins+ NSCLC: Therapy - ClinicalThought - Targeting EGFR Exon 20 in NSCLC

Joshua Sabari, MD, discusses the clinical use of recently approved therapies for EGFR exon 20 insertion mutations in the management of advanced NSCLC, in this Clinical Care Options (CCO) commentary

www.clinicaloptions.com