mRNA기반으로 하는 폐암백신의 임상이 시작되었다.
https://v.daum.net/v/20240823141726402
https://www.biontech.com/int/en/home/pipeline-and-products/pipeline.html
https://jitc.bmj.com/content/11/Suppl_1/A679
BNT116 is an intravenously administered RNA-lipoplex therapeutic cancer vaccine comprising six RNAs each encoding a tumor-associated antigen (TAA) frequently expressed in non-small cell lung cancer (NSCLC). Here, we report preliminary results from patients with advanced unresectable or metastatic NSCLC (ECOG 0–2) receiving BNT116 monotherapy with optional addition of cemiplimab.
Cemiplimab
Cemiplimab, sold under the brand name Libtayo, is a monoclonal antibody medication for the treatment of squamous cell skin cancer. Cemiplimab belongs to a class of drugs that binds to the programmed death receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway.
https://en.wikipedia.org/wiki/Cemiplimab
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